In the study, “Health Effects of Overweight and Obesity in 195 Countries over 25 Years” published in the top medical journal – the New England Journal of Medicine (July 2017), the investigators followed 68.5 million people between 1980 and 2015. The highest level of age-standardized childhood obesity was observed in the United States (12.7%). Also the United States had the highest numbers of obese adults. The prevalence of obesity increased over this period due to increased availability, accessibility, and affordability of energy-dense foods, intense marketing of such foods, and reduced physical activity following urbanization. Obesity accounted for about 4 million deaths and 120 million disability-adjusted life-years worldwide in 2015. Nearly 70% of the deaths were due to cardiovascular disease. The study demonstrates that clinical interventions to reduce the underlying rate of cardiovascular disease could substantially reduce the burden of disease, however, maintaining a normal body weight through healthy life style is mandatory to achieve full benefit.